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Article

Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1.

Virology - 15 Jun 1996

Morrison L A, Knipe D M

Abstract excerpt

We have investigated the mechanisms by which subcutaneous immunization of mice with a replication-defective mutant of herpes simplex virus 1 protects against infection of the eye and latent infection of the trigeminal ganglion following corneal challenge. First, we have shown that immunization reduces the number of trigeminal ganglion neurons in challenged animals that express the latency-associated transcript....

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PMID: 8661391
DOI: 10.1006/viro.1996.0328

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1.PMID 8661391Read ↗

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