Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1.

doi:10.1006/viro.1996.0328

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Article

Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1.

Virology - 15 Jun 1996

Morrison L A, Knipe D M

Abstract excerpt

We have investigated the mechanisms by which subcutaneous immunization of mice with a replication-defective mutant of herpes simplex virus 1 protects against infection of the eye and latent infection of the trigeminal ganglion following corneal challenge. First, we have shown that immunization re...

Topics

Animals
Chlorocebus aethiops
DNA-Binding Proteins
Defective Viruses
Disease Models, Animal
Female
Herpesvirus 1, Human
Humans
Immunization
Keratitis, Herpetic
Mice
Mice, Inbred BALB C
Mutation
Time Factors
Trigeminal Ganglion
Vaccines, Attenuated
Vero Cells
Viral Proteins

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