Article
Herpes simplex virus type 1 latency-associated transcript (LAT) promoter deletion mutants can express a 2-kilobase transcript mapping to the LAT region.
Journal of virology - 1 Dec 1993
Nicosia M, Deshmane S L, Zabolotny J M, Valyi-Nagy T, Fraser N W
Abstract excerpt
The results of studies in several laboratories suggest that a TATA box-containing promoter located in the herpes simplex virus type 1 internal long repeat and long terminal repeat elements drives expression of the latency-associated transcripts (LATs). In the present study, we show that expressio...
Topics
- Animals
- Cells, Cultured
- Chromosome Mapping
- Female
- Genetic Variation
- Herpesvirus 1, Human
- Mice
- Mice, Inbred BALB C
- Mutation
- Promoter Regions, Genetic
- RNA, Messenger
- Sequence Deletion
- Trigeminal Ganglion
- Virus Latency
