Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Simultaneous Detection of Herpes Simplex Virus Type 1 Latent and Lytic Transcripts in Brain Tissue

1 Jan 2022

Abstract excerpt

Neurotrophic herpes simplex virus type 1 (HSV-1) establishes lifelong latent infection in humans. Accumulating studies indicate that HSV-1, a risk factor of neurodegenerative diseases, exacerbates the sporadic Alzheimer's disease (AD). The analysis of viral genetic materials via genomic sequencing and quantitative PCR (qPCR) is the current approach used for the detection of HSV-1; however, this approach is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to interferon and immune responses
Share to RNA regulation and disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35164537
DOI: 10.1177/17590914211053505

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Simultaneous Detection of Herpes Simplex Virus Type 1 Latent and Lytic Transcripts in Brain TissuePMID 35164537Read ↗

Varicella-Zoster Virus Transcriptome in Latently Infected Human GangliaSemantic proximity Read ↗

Insights into the pathogenesis of herpes simplex encephalitis from mouse models.Semantic proximity Read ↗

No evidence for aberrant expression of amyloid β and phosphorylated tau proteins in herpes simplex virus-infected human neurons <i>in vivo</i>Semantic proximity Read ↗

HSV-1 Infection Alters <i>MAPT</i> Splicing and Promotes Tau Pathology in Neural Models of Alzheimer’s DiseaseSemantic proximity Read ↗

Neurodegeneration in human brain organoids infected with herpes simplex virus type 1Semantic proximity Read ↗

Spatiotemporal dynamics of alphaherpesviral latency and reactivation in the murine central nervous systemSemantic proximity Read ↗

Laser-Capture Microdissection: Refining Estimates of the Quantity and Distribution of Latent Herpes Simplex Virus 1 and Varicella-Zoster Virus DNA in Human Trigeminal Ganglia at the Single-Cell LevelSemantic proximity Read ↗

Herpes Simplex Virus and Interferon Signaling Induce Novel Autophagic Clusters in Sensory NeuronsSemantic proximity Read ↗

A spliced latency-associated VZV transcript maps antisense to the viral transactivator gene 61Semantic proximity Read ↗

Latency Entry of Herpes Simplex Virus 1 Is Determined by the Interaction of Its Genome with the Nuclear Environment.Semantic proximity Read ↗

Expression of Herpes Simplex Virus 1-Encoded MicroRNAs in Human Trigeminal Ganglia and Their Relation to Local T-Cell InfiltratesSemantic proximity Read ↗

Lytic Gene Expression Is Frequent in HSV-1 Latent Infection and Correlates with the Engagement of a Cell-Intrinsic Transcriptional ResponseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.