Identification of genes required for Drosophila eye development using a phenotypic enhancer-trap.

doi:10.1073/pnas.94.17.9220

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Article

Identification of genes required for Drosophila eye development using a phenotypic enhancer-trap.

Proceedings of the National Academy of Sciences of the United States of America - 19 Aug 1997

Pignoni F, Hu B, Zipursky S L

Abstract excerpt

A novel method of P-element mutagenesis is described for the isolation of mutants affecting the development of the Drosophila compound eye. It exploits the interaction between the Bride of Sevenless (Boss) ligand and the Sevenless (Sev) receptor tyrosine kinase that triggers the formation of the...

Topics

Animals
Drosophila melanogaster
Eye
Gene Expression Regulation, Developmental
Genes, Insect
Mutation
Phenotype

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