Article
[Molecular genetic analysis of sporadic Alzheimer's disease].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics - 1 Jun 1993
Nishiwaki Y, Nagano K, Kamino K, Katsuya T, Tanabe H, Nishimura T, Miki T, Ogihara T
Abstract excerpt
The authors report the clinical findings and the results of molecular genetic analysis of 8 patients with sporadic Alzheimer's disease. Differential diagnosis was carried out on the basis of familial history, laboratory data, brain imaging analysis using CT, MRI and SPECT. According to the clinic...
Topics
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Amyloid beta-Protein Precursor
- DNA
- Diagnosis, Differential
- Female
- Humans
- Magnetic Resonance Imaging
- Middle Aged
- Mutation
- Polymerase Chain Reaction
- PrPSc Proteins
- Prions
- Tomography, Emission-Computed, Single-Photon
