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Article

Sequence analysis of presenilin-1 gene mutation in Japanese Alzheimer's disease patients.

Neuroscience letters - 1 Nov 1996

Tanahashi H, Kawakatsu S, Kaneko M, Yamanaka H, Takahashi K, Tabira T

Abstract excerpt

The mutations of presenilins (PSs) gene and their clinicopathological correlations to Alzheimer's disease (AD) have lately attracted considerable attention. In this report we analyzed fifteen Japanese familial Alzheimer's disease (FAD) including 12 early-onset FAD and 13 sporadic AD patients for the mutation of PS-1 gene by direct sequence analysis. We found the mutations, G384A, E280A in two FAD and H163R in one...

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Source

Identifiers

PMID: 8945747
DOI: 10.1016/s0304-3940(96)13138-4

Genes

APP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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