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[Mutation analysis of amyloid precursor protein in early-onset familial Alzheimer's disease].

Nihon rinsho. Japanese journal of clinical medicine - 1 Sept 1993

Naruse S, Fujigasaki H, Miyatake T

Abstract excerpt

Recently, three different mutations have been found at codon 717 of the amyloid precursor protein (APP) gene, changing the native valine to isoleucine, phenylalanine and glycine in some familial Alzheimer's disease (FAD) kindreds. More recently, some other mutations have also been reported at codons 670 and 671 (double mutation), and codon 692. As analysis of coding region except exon 16 and 17 has been...

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Source

Identifiers

PMID: 8411726

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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