Article
Molecular heterogeneity of autosomal dominant cerebellar ataxia: analysis of flanking microsatellites of the spinocerebellar ataxia 1 locus in a northern European family unequivocally demonstrates non-linkage.
Human genetics - 1 May 1993
Lunkes A, Gispert S, Enczmann J, Auburger G
Abstract excerpt
This study addresses the question whether the different forms of autosomal dominant cerebellar ataxia (ADCA) are related to different ethnic/geographical regions in Europe. One mutation in families originating from Holland, Prussia and Italy has previously been localized to chromosome 6p (SCA1 lo...
Topics
- Cerebellar Ataxia
- Chromosomes, Human, Pair 6
- DNA, Satellite
- Denmark
- Female
- Genes, Dominant
- Genetic Linkage
- Genetic Variation
- HLA-DR Antigens
- Humans
- Male
- Pedigree
- Polymorphism, Restriction Fragment Length
- Spinocerebellar Degenerations