The Machado-Joseph disease locus is different from the spinocerebellar ataxia locus (SCA1).

doi:10.1016/0888-7543(92)90168-r

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Article

The Machado-Joseph disease locus is different from the spinocerebellar ataxia locus (SCA1).

Genomics - 1 Jul 1992

Carson W J, Radvany J, Farrer L A, Vincent D, Rosenberg R N, MacLeod P M, Rouleau G A

Abstract excerpt

Machado-Joseph disease (MJD) is an autosomal dominant neurodegenerative spinocerebellar ataxia that has been described primarily in families of Azorean or Portuguese descent. MJD and chromosome 6p-linked spinocerebellar ataxia (SCA1) are difficult to differentiate clinically, and it has been sugg...

Topics

Alleles
Chromosomes, Human, Pair 6
Genes, Dominant
Genetic Markers
Humans
Lod Score
Spinocerebellar Degenerations

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