Autosomal dominant spinocerebellar ataxia (SCA) in a Siberian founder population: assignment to the SCA1 locus.

doi:10.1006/exnr.1994.1070

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Article

Autosomal dominant spinocerebellar ataxia (SCA) in a Siberian founder population: assignment to the SCA1 locus.

Experimental neurology - 1 Apr 1994

Lunkes A, Goldfarb L G, Platonov F A, Alexeev V P, Duenas-Barajas E, Gajdusek D C, Auburger G

Abstract excerpt

In seven families from a Siberian founder population with autosomal dominant spinocerebellar ataxia (SCA) genetic analysis of the polymorphisms flanking the SCA1 locus on chromosome 6p showed allelic association with disease inheritance. While the association was absolute in the case of microsate...

Topics

Alleles
Chromosome Mapping
Chromosomes, Human, Pair 6
Female
Genes, Dominant
Humans
Male
Pedigree
Siberia
Spinocerebellar Degenerations

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