Genetic heterogeneity of autosomal dominant cerebellar ataxia type 1: clinical and genetic analysis of 10 French families.

doi:10.1212/wnl.43.6.1131

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Article

Genetic heterogeneity of autosomal dominant cerebellar ataxia type 1: clinical and genetic analysis of 10 French families.

Neurology - 1 Jun 1993

Khati C, Stevanin G, Durr A, Chneiweiss H, Belal S, Seck A, Cann H, Brice A, Agid Y

Abstract excerpt

We performed linkage analysis between the gene responsible for spinal cerebellar ataxia 1 (SCA1) and the highly polymorphic chromosome 6 locus, D6S89, in 10 French families with autosomal dominant cerebellar ataxia (ADCA) type 1. These families were clinically indistinguishable except for one fam...

Topics

Adult
Alleles
Cerebellar Ataxia
Female
France
Genetic Linkage
Humans
Male
Middle Aged
Pedigree
Polymorphism, Genetic

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