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Article

Autosomal dominant ataxia: genetic evidence for locus heterogeneity from a Cuban founder-effect population.

American journal of human genetics - 1 Jun 1990

Auburger G, Diaz G O, Capote R F, Sanchez S G, Perez M P, del Cueto M E, Meneses M G, Farrall M, Williamson R, Chamberlain S

Abstract excerpt

The locus for autosomal dominant ataxia with a diagnosis of olivo-ponto-cerebellar atrophy at autopsy has been previously assigned to chromosome 6p. However, evidence for two alternative locations has been reported. We have recently described a large potential founder-effect population of such pa...

Topics

Chromosomes, Human, Pair 6
Cuba
Female
Genes, Dominant
Genetic Linkage
HLA Antigens
Humans
Lod Score
Male
Mutation
Pedigree
Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spinocerebellar Degenerations

Source

Open in PubMed Open full text

Identifiers

PMID: 1971152
PMCID: PMC1683834

Genes

GLO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1971152-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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