Article
Cloning of the Drosophila cyclodiene insecticide resistance gene: a novel GABAA receptor subtype?
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology - 1 Jan 1993
Ffrench-Constant R H
Abstract excerpt
1. gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in both vertebrates and invertebrates. GABAA receptors are composed of a number of different subunits that assemble to form a chloride ionophore. 2. Several subunit types, alpha, beta, gamma, delta and rho have been cloned from vertebrates, but until recently these receptors have remained uncloned from invertebrates. 3. GABAA receptors form...
Topics
- Animals
- Cloning, Molecular
- Drosophila
- Insecticide Resistance
- Insecticides
- Mutation
- Receptors, GABA-A