Article
Conservation of cyclodiene insecticide resistance-associated mutations in insects.
Insect molecular biology - 1 Jan 1993
Thompson M, Steichen J C, ffrench-Constant R H
Abstract excerpt
Cyclodiene insecticide resistance has accounted for over 60% of reported cases of insecticide resistance. In Drosophila melanogaster resistance is associated with a single base pair substitution in the GABA receptor/chloride ion channel gene Rdl. This substitution predicts the replacement of an alanine with a serine in the second membrane spanning domain, the region thought to line the chloride ion channel pore....
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