Article
Cloning and sequencing of the cyclodiene insecticide resistance gene from the yellow fever mosquito Aedes aegypti. Conservation of the gene and resistance associated mutation with Drosophila.
FEBS letters - 5 Jul 1993
Thompson M, Shotkoski F, ffrench-Constant R
Abstract excerpt
In order to examine the conservation of the mechanism of cyclodiene insecticide resistance between species we cloned a cDNA from the yellow fever mosquito Aedes aegypti homologous to the resistance gene Rdl in Drosophila. In D. melanogaster, resistance to cyclodienes and picrotoxinin is caused by...
Topics
- Aedes
- Amino Acid Sequence
- Animals
- Cloning, Molecular
- Conserved Sequence
- Drosophila Proteins
- Drosophila melanogaster
- Insecticide Resistance
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Receptors, GABA-A
- Restriction Mapping
- Sequence Homology, Amino Acid