GABA receptor minigene rescues insecticide resistance phenotypes in Drosophila.

doi:10.1006/jmbi.1995.0547

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Article

GABA receptor minigene rescues insecticide resistance phenotypes in Drosophila.

Journal of molecular biology - 20 Oct 1995

Stilwell G E, Rocheleau T, ffrench-Constant R H

Abstract excerpt

A single point mutation within the GABA receptor gene Resistance to dieldrin (Rdl) confers a high level of resistance to cyclodiene insecticides in a wide range of insects. Previous studies have shown partial rescue of the susceptible phenotype via germline transformation of a 36 kb cosmid coding...

Topics

Animals
Chromosome Mapping
Cosmids
Dieldrin
Drosophila
Genes, Insect
Genotype
Heterozygote
Insecticide Resistance
Insecticides
Phenotype
Point Mutation
Promoter Regions, Genetic
RNA Splicing
Receptors, GABA

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