PrP polymorphisms associated with natural scrapie discovered by denaturing gradient gel electrophoresis.

doi:10.1006/geno.1993.1006

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

PrP polymorphisms associated with natural scrapie discovered by denaturing gradient gel electrophoresis.

Genomics - 1 Jan 1993

Laplanche J L, Chatelain J, Westaway D, Thomas S, Dussaucy M, Brugere-Picoux J, Launay J M

Abstract excerpt

Scrapie is a transmissible degenerative disease of the central nervous system occurring naturally in sheep and goats. An abnormal protease-resistant form of the host-encoded prion protein (PrP) accumulates in the brains of affected animals. As Sip, a gene controlling the incubation period of expe...

Topics

Amino Acid Sequence
Animals
Base Sequence
Codon
DNA
Electrophoresis, Polyacrylamide Gel
Genotype
Membrane Glycoproteins
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic
PrPSc Proteins
Prions
Scrapie
Sheep

Source

Open in PubMed

Identifiers

PMID: 8094373
DOI: 10.1006/geno.1993.1006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8094373-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics