Article
Polymorphism of prion protein gene (PRNP) in Nigerian sheep.
Prion - 1 Dec 2023
Adeola Adeniyi C, Bello Semiu F, Abdussamad Abdussamad M, Mark Akanbi I, Sanke Oscar J, Onoja Anyebe B, Nneji Lotanna M, Abdullahi Nasiru, Olaogun Sunday C, Rogo Lawal D, Mangbon Godwin F, Pedro Shamsudeen L, Hiinan Manasseh P, Mukhtar Muhammad M, Ibrahim Jebi, Saidu Hayatu, Dawuda Philip M, Bala Rukayya K, Abdullahi Hadiza L, Salako Adebowale E, Kdidi Samia, Yahyaoui Mohamed Habib, Yin Ting-Ting
Abstract excerpt
Polymorphism of the prion protein gene (PRNP) gene determines an animal's susceptibility to scrapie. Three polymorphisms at codons 136, 154, and 171 have been linked to classical scrapie susceptibility, although many variants of PRNP have been reported. However, no study has investigated scrapie susceptibility in Nigerian sheep from the drier agro-climate zones. In this study, we aimed to identify PRNP...
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