Article
Racial differences in restriction fragment length polymorphisms and messenger RNA inducibility of the human CYP1A1 gene.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2000
Cosma G, Crofts F, Currie D, Wirgin I, Toniolo P, Garte S J
Abstract excerpt
Recent studies have examined the relationship between genetic polymorphisms of the human cytochrome P-4501A1 (CYP1A1) gene and lung cancer susceptibility. We have quantified genotypic frequencies and measured gene expression in the CYP1A1 gene within racially diverse groups in order to determine the relationship between genotype and transcriptional regulation of the CYP1A1 gene. Lymphocytes were obtained from 68...
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