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Article

Functional significance of different human CYP1A1 genotypes.

Carcinogenesis - 1 Dec 1994

Crofts F, Taioli E, Trachman J, Cosma G N, Currie D, Toniolo P, Garte S J

Abstract excerpt

At least two different polymorphisms in the human CYP1A1 gene have been associated with an increased risk for tobacco-related lung cancer; however, the functional significance of these polymorphisms has not been determined. We measured CYP1A1 genotypes, gene expression levels and enzymatic activity levels in mitogen-stimulated lymphocytes to determine whether genetic polymorphisms in CYP1A1 alter transcriptional...

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Identifiers

PMID: 8001264
DOI: 10.1093/carcin/15.12.2961

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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