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Article

The NS2 Polypeptide of Parvovirus MVM Is Required for Capsid Assembly in Murine Cells

1 May 1997

Abstract excerpt

Mutants of minute virus of mice (MVM) which express truncated forms of the NS2 polypeptide are known to exhibit a host range defect, replicating productively in transformed human cells but not in cells from their normal murine host. To explore this deficiency we generated viruses with translation termination codons at various positions in the second exon of NS2. In human cells these mutants were viable, but...

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Identifiers

PMID: 9168889
DOI: 10.1006/viro.1997.8545

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