Article
Mouse polyomavirus late region mutants expressing a defective VP2 capsid protein exhibit an enhanced viral DNA replication.
Virus genes - 1 Mar 1994
Melucci-Vigo G, Magnusson G, Risuleo G
Abstract excerpt
We have constructed mouse polyomavirus mutants with deletions or insertions in the late region. These viral constructs exhibit two different phenotypes, characterized by a differential replication ability. The first type shows a twofold higher level of DNA synthesis with respect to wild type, while mutants of the second type are virtually unable to replicate. In this paper we investigate the replicative behavior...
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