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Article

Mouse polyomavirus late region mutants expressing a defective VP2 capsid protein exhibit an enhanced viral DNA replication.

Virus genes - 1 Mar 1994

Melucci-Vigo G, Magnusson G, Risuleo G

Abstract excerpt

We have constructed mouse polyomavirus mutants with deletions or insertions in the late region. These viral constructs exhibit two different phenotypes, characterized by a differential replication ability. The first type shows a twofold higher level of DNA synthesis with respect to wild type, whi...

Topics

Animals
Capsid
Capsid Proteins
DNA Replication
Genes, Viral
Mice
Mutation
Phenotype
Polyomavirus
Viral Structural Proteins
Virus Replication

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8073634
DOI: 10.1007/BF01703070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8073634-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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