Article
Identification of a novel HLA-B27 subtype by restriction analysis of a cytotoxic gamma delta T cell clone.
Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 1994
Del Porto P, D'Amato M, Fiorillo M T, Tuosto L, Piccolella E, Sorrentino R
Abstract excerpt
Seven HLA-B27 alleles are known, which share the same allospecificity, but differ by one to six amino acid substitutions. Herein, we describe a novel HLA-B27 allele, provisionally named B27-ci, which is expressed by an individual from whom a B27-restricted gamma delta T cell clone has been derive...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Clone Cells
- Cloning, Molecular
- Cytotoxicity, Immunologic
- DNA Primers
- DNA, Complementary
- Female
- HLA-B27 Antigen
- Humans
- Male
