Article
Transduction of a human RNA sequence by poliovirus.
Journal of virology - 1 Oct 1994
Charini W A, Todd S, Gutman G A, Semler B L
Abstract excerpt
Cells infected with poliovirus express a virally encoded polyprotein which undergoes self-mediated cleavage into structural and nonstructural viral proteins. Most of these cleavages are catalyzed by the 3C proteolytic domain of the polyprotein. Polyprotein synthesized in vitro from an RNA templat...
Topics
- Amino Acid Sequence
- Base Sequence
- HeLa Cells
- Humans
- Methionine
- Models, Genetic
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Phenotype
- Poliovirus
- Protein Biosynthesis
- RNA, Ribosomal, 28S
- RNA, Viral
