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Article

[Lack of association between alcoholism and alleles in the delta-aminolevulinic acid dehydratase (ALAD) gene].

Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studies & drug dependence - 1 Jun 1994

Muramatsu T, Harada S, Higuchi S, Murayama M, Matsushita S, Hayashida M

Abstract excerpt

delta-Aminolevulinic acid dehydratase (ALAD) is the second enzyme in the heme biosynthetic pathway and catalyzes two molecules of delta-aminolevulinate (ALA), which is a potent agonist for GABA autoreceptors. ALAD has two common alleles and thus consists of three distinct isozymes, designated 1-1, 1-2, and 2-2. It has been shown recently that ALAD1 allele is associated with alcoholic liver injury. This...

Topics

Adult
Alcoholism
Alleles
DNA
Female
Genotype
Humans
Male
Middle Aged
Polymorphism, Genetic
Porphobilinogen Synthase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8080400

Genes

ALAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8080400-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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