Article
Association between a polymorphism of aminolevulinate dehydrogenase (ALAD) gene and blood lead levels in Japanese subjects.
International journal of environmental research and public health - 1 Mar 2009
Miyaki Koichi, Lwin Htay, Masaki Katsunori, Song Yixuan, Takahashi Yoshimitsu, Muramatsu Masaaki, Nakayama Takeo
Abstract excerpt
This cross-sectional study investigated the relationship between the aminolevulinate dehydrogenase (ALAD) genotype and blood lead levels among 101 Japanese workers. Blood lead concentration measurement, biomarkers, and genotyping were performed. The minor allele frequency (MAF) for ALAD (ALAD2) was 0.08. Although the blood lead level in the subjects with heterozygous GC genotype was significantly higher than...
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