Article
Mood-lowering effect of tryptophan depletion. Enhanced susceptibility in young men at genetic risk for major affective disorders.
Archives of general psychiatry - 1 Sept 1994
Benkelfat C, Ellenbogen M A, Dean P, Palmour R M, Young S N
Abstract excerpt
METHODS: A double-blind placebo-controlled cross-over study in which plasma tryptophan was manipulated by administration of a tryptophan-deficient amino acid mixture. In the placebo condition, all subjects received a nutritionally balanced amino acid mixture that contained tryptophan. To further...
Topics
- Adolescent
- Adult
- Affect
- Alcoholism
- Amino Acids
- Depressive Disorder
- Double-Blind Method
- Family
- Genetic Markers
- Humans
- Male
- Phenotype
- Placebos
- Psychiatric Status Rating Scales
- Serotonin
- Substance-Related Disorders
- Tryptophan