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Article

Differential effects of 5-HTTLPR genotypes on mood, memory, and attention bias following acute tryptophan depletion and stress exposure.

Psychopharmacology - 1 May 2009

Firk Christine, Markus C Rob

Abstract excerpt

RATIONALE: Polymorphisms of the serotonin transporter gene (5-HTTLPR) may be associated with increased vulnerability to acute tryptophan depletion (ATD) and depression vulnerability especially following stressful life events. OBJECTIVE: The aim of the present study was to investigate the effects of ATD in subjects with different 5-HTTLPR profiles before and after stress exposure on affective and...

Topics

Affect
Attention
Cross-Over Studies
Double-Blind Method
Female
Genotype
Humans
Male
Memory
Polymorphism, Genetic
Serotonin Plasma Membrane Transport Proteins
Stress, Psychological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tryptophan

Young Adult

Source

Identifiers

PMID: 19083208
DOI: 10.1007/s00213-008-1428-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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