Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mood effects of 24-hour tryptophan depletion in healthy first-degree relatives of patients with affective disorders.

Biological psychiatry - 15 Aug 1999

Klaassen T, Riedel W J, van Someren A, Deutz N E, Honig A, van Praag H M

Abstract excerpt

BACKGROUND: Acute tryptophan (TRP) depletion was evaluated in healthy volunteers with or without a family history of major affective disorder (FH+ versus FH-). METHODS: Twenty-seven subjects (16 FH+, 11 FH-) received 100 g of an amino acid mixture with and without TRP according to a placebo-contr...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cross-Over Studies
Share to Depression
Share to Double-Blind Method

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mood Disorders

Share to Psychiatric Status Rating Scales

Share to Reference Values

Share to Sex Characteristics

Share to Tryptophan

Source

Identifiers

PMID: 10459398
DOI: 10.1016/s0006-3223(99)00082-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10459398-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mood effects of 24-hour tryptophan depletion in healthy first-degree relatives of patients with affective disorders.PMID 10459398Read ↗

Mood-lowering effect of tryptophan depletion. Enhanced susceptibility in young men at genetic risk for major affective disorders.Semantic proximity Read ↗

Harnessing Dietary Tryptophan: Bridging the Gap Between Neurobiology and Psychiatry in Depression ManagementSemantic proximity Read ↗

Tryptophan depletion and depressive vulnerability.Semantic proximity Read ↗

Acute tryptophan depletion effects on the vertex and late positive potentials to emotional faces in individuals with a family history of depression.Semantic proximity Read ↗

Tryptophan Depletion, Serotonin, and Depression: Where Do We Stand?Semantic proximity Read ↗

Harnessing Plant-Derived Tryptophan: Bridging the Gap Between Neurobiology and Psychiatry in Depression ManagementSemantic proximity Read ↗

Targeting tryptophan hydroxylase 2 in affective disorder.Semantic proximity Read ↗

Folic acid supplementation for prevention of mood disorders in young people at familial risk: a randomised, double blind, placebo controlled trial.Semantic proximity Read ↗

Effects of rapid tryptophan depletion on mood and urge to drink in patients with co-morbid major depression and alcohol dependence.Semantic proximity Read ↗

Alteration of frontal EEG asymmetry during tryptophan depletion predicts future depression.Semantic proximity Read ↗

Acute tryptophan depletion. Part II: clinical effects and implications.Semantic proximity Read ↗

Tryptophan hydroxylase gene (TPH1) and peripheral tryptophan levels in depression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.