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Article

Mammalian alpha 1-subunit of Na(+)-K(+)-ATPase does not need its amino terminus to maintain cell viability.

The American journal of physiology - 1 Aug 1994

Shanbaky N M, Pressley T A

Abstract excerpt

The amino terminus of the catalytic alpha-subunit from Na(+)-K(+)-adenosinetriphosphatase (ATPase) is not conserved among the various isoforms and species sequenced to date, yet it always includes a lysine-rich motif. To investigate the functional role played by this highly charged region, we altered the amino terminus of rat alpha 1 and evaluated the ability of the mutant to sustain cell viability. Nucleotide...

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PMID: 8074192
DOI: 10.1152/ajpcell.1994.267.2.C590

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