Article
Dysregulation of interferon-γ-mediated signalling pathway in intestinal epithelial cells by<i>Cryptosporidium parvum</i>infection
15 May 2009
Abstract excerpt
The apicomplexan parasite Cryptosporidium parvum, the agent of cryptosporidiosis, primarily infects and reproduces in enterocytes. Interferon (IFN)-gamma is important for early control of the infection and acts directly on enterocytes to inhibit parasite development, although complete inhibition is not obtained. Addressing this latter observation, an investigation was made of the modulatory effect of C. parvum...
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