Article
Alteration of the intestinal intraepithelial lymphocytes during total parenteral nutrition.
The Journal of surgical research - 1 Oct 1998
Kiristioglu I, Teitelbaum D H
Abstract excerpt
Total parenteral nutrition (TPN) may cause increased rates of bacterial translocation (BT), possibly due to a loss of epithelial integrity. Cultured epithelial cells have been shown to lose tight junction integrity with interferon gamma (INF-gamma) an action which may be blocked by transforming growth factor beta (TGF-beta). Because intraepithelial lymphocytes (IEL) are a rich source of these cytokines in the...
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