Article
Search for a schizophrenia susceptibility locus on human chromosome 22.
American journal of medical genetics - 15 Jun 1994
Polymeropoulos M H, Coon H, Byerley W, Gershon E S, Goldin L, Crow T J, Rubenstein J, Hoff M, Holik J, Smith A M
Abstract excerpt
We used 10 highly informative DNA polymorphic markers and genetic linkage analysis to examine whether a gene locus predisposing to schizophrenia is located on chromosome 22, in 105 families with schizophrenia and schizoaffective disorder. The LOD score method, including analysis for heterogeneity...
Topics
- Chromosome Mapping
- Chromosomes, Human, Pair 22
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Lod Score
- Male
- Pedigree
- Schizophrenia