Article
Family-based association study of markers on chromosome 22 in schizophrenia using African-American, European-American, and Chinese families.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jul 2003
Takahashi Sakae, Cui Yu-Hu, Kojima Takuya, Han Yong-Hua, Zhou Ru-Lum, Kamioka Masashi, Yu Shun-Ying, Matsuura Masato, Matsushima Eisuyke, Wilcox Marsha, Arinami Tadao, Shen Yu-Cun, Faraone Stephen V, Tsuang Ming T
Abstract excerpt
Several studies suggest that loci at chromosome 22q11.2-q13 might be linked to susceptibility to schizophrenia. Here we performed family-based association studies on chromosome 22q using 12 DNA microsatellite markers in African-American, European-American, and Chinese pedigrees. The marker D22S683 showed significant linkage and association with schizophrenia in not only the European-American sample but also in a...
Topics
- Adult
- Asian People
- Black People
- Chromosome Mapping
- Chromosomes, Human, Pair 22
- Female
- Genetic Linkage
- Genetic Markers
- Genotype