Article
Genome scan of schizophrenia.
The American journal of psychiatry - 1 Jun 1998
Levinson D F, Mahtani M M, Nancarrow D J, Brown D M, Kruglyak L, Kirby A, Hayward N K, Crowe R R, Andreasen N C, Black D W, Silverman J M, Endicott J, Sharpe L, Mohs R C, Siever L J, Walters M K, Lennon D P, Jones H L, Nertney D A, Daly M J, Gladis M, Mowry B J
Abstract excerpt
OBJECTIVE: The goal of this study was to identify chromosomal regions likely to contain schizophrenia susceptibility genes. METHOD: A genomewide map of 310 microsatellite DNA markers with average spacing of 11 centimorgans was genotyped in 269 individuals--126 of them with schizophrenia-related psychoses--from 43 pedigrees. Nonparametric linkage analysis was used to assess the pattern of allele sharing at each...
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