Article
A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility locus for schizophrenia at chromosome 22q12. Schizophrenia Collaborative Linkage Group (Chromosome 22).
American journal of medical genetics - 16 Feb 1996
Gill M, Vallada H, Collier D, Sham P, Holmans P, Murray R, McGuffin P, Nanko S, Owen M, Antonarakis S, Housman D, Kazazian H, Nestadt G, Pulver A E, Straub R E, MacLean C J, Walsh D, Kendler K S, DeLisi L, Polymeropoulos M, Coon H, Byerley W, Lofthouse R, Gershon E, Read C M
Abstract excerpt
Several groups have reported weak evidence for linkage between schizophrenia and genetic markers located on chromosome 22q using the lod score method of analysis. However these findings involved different genetic markers and methods of analysis, and so were not directly comparable. To resolve thi...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 22
- Disease Susceptibility
- Genetic Heterogeneity
- Genetic Markers
- Humans
- Schizophrenia