Article
ebi regulates epidermal growth factor receptor signaling pathways in Drosophila.
Genes & development - 15 Apr 1999
Dong X, Tsuda L, Zavitz K H, Lin M, Li S, Carthew R W, Zipursky S L
Abstract excerpt
ebi regulates the epidermal growth factor receptor (EGFR) signaling pathway at multiple steps in Drosophila development. Mutations in ebi and Egfr lead to similar phenotypes and show genetic interactions. However, ebi does not show genetic interactions with other RTKs (e.g., torso) or with components of the canonical Ras/MAP kinase pathway. ebi encodes an evolutionarily conserved protein with a unique amino...
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