Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Receptor binding and signal transduction are dissociable functions requiring different sites on follicle-stimulating hormone.

Endocrinology - 1 Dec 1994

Valove F M, Finch C, Anasti J N, Froehlich J, Flack M R

Abstract excerpt

Separate sites for glycoprotein hormone receptor binding and signal transduction have yet to be elucidated. In general, certain peptide regions are thought to be critical for receptor binding, whereas the oligosacharides are thought to be important for signal transduction. Using site-directed mut...

Topics

Follicle Stimulating Hormone
Humans
Mutagenesis, Site-Directed
Mutation
Oligosaccharides
Receptors, FSH
Recombinant Proteins
Signal Transduction

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7988456
DOI: 10.1210/endo.135.6.7988456

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7988456-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Receptor binding and signal transduction are dissociable functions requiring different sites on follicle-stimulating hormone.PMID 7988456Read ↗

Specific roles for the asparagine-linked carbohydrate residues of recombinant human follicle stimulating hormone in receptor binding and signal transduction.Semantic proximity Read ↗

Specific roles for the asparagine-linked carbohydrate residues of recombinant human follicle stimulating hormone in receptor binding and signal transductionSemantic proximity Read ↗

Role of the intracellular domains of the human FSH receptor in G(alphaS) protein coupling and receptor expression.Semantic proximity Read ↗

Differential responses of an invariant region in the ectodomain of three glycoprotein hormone receptors to mutagenesis and assay conditions.Semantic proximity Read ↗

The tale of follitropin receptor diversity: a recipe for fine tuning gonadal responses?Semantic proximity Read ↗

Rescue of Cell Surface Expression and Signaling of Mutant Follicle-Stimulating Hormone Receptors.Semantic proximity Read ↗

Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer.Semantic proximity Read ↗

Trans-activation of mutant follicle-stimulating hormone receptors selectively generates only one of two hormone signals.Semantic proximity Read ↗

Biased Signaling and Allosteric Modulation at the FSHRSemantic proximity Read ↗

In Vivo and In Vitro Impact of Carbohydrate Variation on Human Follicle-Stimulating Hormone FunctionSemantic proximity Read ↗

Dominant negative effects of human follicle-stimulating hormone receptor expression-deficient mutants on wild-type receptor cell surface expression. Rescue of oligomerization-dependent defective receptor expression by using cognate decoys.Semantic proximity Read ↗

Molecular cloning, structure, and expression of a testicular follitropin receptor with selective alteration in the carboxy terminus that affects signaling function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.