Article
Chromosome 17 abnormalities and TP53 mutations in adult soft tissue sarcomas.
The American journal of pathology - 1 Aug 1994
Latres E, Drobnjak M, Pollack D, Oliva M R, Ramos M, Karpeh M, Woodruff J M, Cordon-Cardo C
Abstract excerpt
This study was designed to determine the frequency of structural genetic abnormalities of chromosome 17 and the incidence of TP53 mutations as they relate to the biological behavior of adult soft tissue sarcomas. We analyzed a group of 73 soft tissue sarcomas of adults that were clinically and pa...
Topics
- Alleles
- Cell Nucleus
- Chromosome Aberrations
- Chromosome Disorders
- Chromosomes, Human, Pair 17
- Gene Rearrangement
- Genes, p53
- Heterozygote
- Humans
- Mutation
- Sarcoma
- Soft Tissue Neoplasms
- Tumor Suppressor Protein p53