Article
Structure and expression of the hairless gene of mice.
Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 1994
Cachon-Gonzalez M B, Fenner S, Coffin J M, Moran C, Best S, Stoye J P
Abstract excerpt
The hairless mutation of mice was caused by insertion of a murine leukemia virus. Starting with sequences flanking the provirus, a series of overlapping clones surrounding the viral integration site were obtained. By using a combination of sequencing, PCR, and exon-trapping techniques, the hairless gene was identified. It encodes a predicted protein of 1182 amino acids, including a potential zinc-finger domain....
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- Exons
- Gene Expression
- In Situ Hybridization
- Leukemia Virus, Murine
- Mice
- Mice, Hairless
- Molecular Sequence Data