Article
A novel nonsense mutation and polymorphisms in the mouse hairless gene.
The Journal of investigative dermatology - 1 Jun 2005
Zhang Jin-Tao, Fang Sheng-Guo, Wang Chun-Yao
Abstract excerpt
A novel autosomal recessive mutation arose spontaneously in a breeding colony of Chinese Kunming mice. The characteristics of these mutant mice include progressive irreversible hair loss soon after birth, rhinocerotic appearance, and shorter life span. Histological evaluation of skin revealed the homogeneous enlargement of utriculi, and the formation of several rows of large cysts. Sequencing the complete cDNA of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
