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Article

Recapitulation of the hairless mouse phenotype using catalytic oligonucleotides: implications for permanent hair removal.

Experimental dermatology - 1 Mar 2004

Cserhalmi-Friedman Peter B, Panteleyev Andrey A, Christiano Angela M

Abstract excerpt

Ribozyme technology is widely used to target mRNA in a sequence-specific fashion and thus change the expression pattern of cells or tissues. While the goal of mRNA targeting is usually the cleavage of mutant mRNAs with the prospect of gene therapy for inherited diseases, in certain instances, targeting of wild-type genes can be used therapeutically. Lack of expression of the mouse hairless gene due to inherited...

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PMID: 14987255
DOI: 10.1111/j.0906-6705.2004.0143.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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