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Article

Alopecia universalis associated with a mutation in the human hairless gene.

Science (New York, N.Y.) - 30 Jan 1998

Ahmad W, Faiyaz ul Haque M, Brancolini V, Tsou H C, ul Haque S, Lam H, Aita V M, Owen J, deBlaquiere M, Frank J, Cserhalmi-Friedman P B, Leask A, McGrath J A, Peacocke M, Ahmad M, Ott J, Christiano A M

Abstract excerpt

There are several forms of hereditary human hair loss, known collectively as alopecias, the molecular bases of which are entirely unknown. A kindred with a rare, recessively inherited type of alopecia universalis was used to search for a locus by homozygosity mapping, and linkage was established in a 6-centimorgan interval on chromosome 8p12 (the logarithm of the odds favoring linkage score was 6.19). The human...

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PMID: 9445480
DOI: 10.1126/science.279.5351.720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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