HLA-D alleles associated with generalized disease, localized disease, and putative immunity in Onchocerca volvulus infection.

doi:10.1073/pnas.91.16.7515

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Article

HLA-D alleles associated with generalized disease, localized disease, and putative immunity in Onchocerca volvulus infection.

Proceedings of the National Academy of Sciences of the United States of America - 2 Aug 1994

Meyer C G, Gallin M, Erttmann K D, Brattig N, Schnittger L, Gelhaus A, Tannich E, Begovich A B, Erlich H A, Horstmann R D

Abstract excerpt

Human infections with the tissue nematode Onchocerca volvulus result in a variety of clinical conditions that possibly include protective immunity. In a West African area hyperendemic for human onchocerciasis, 120 residents were classified according to clinical and laboratory findings as presenting with generalized onchocerciasis, localized onchocerciasis, or as being putatively immune. The three groups differed...

Topics

Adolescent
Adult
Alleles
Animals
Child
Genes, MHC Class II
HLA-D Antigens
HLA-DP Antigens
HLA-DQ Antigens
HLA-DR Antigens
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunity

Immunoglobulin E

Liberia

Middle Aged

Onchocerca volvulus

Onchocerciasis

Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 8052611
DOI: 10.1073/pnas.91.16.7515
PMCID: PMC44432

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8052611-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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