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Identification of three immunodominant motifs with atypical isotype profile scattered over the Onchocerca volvulus proteome

26 Jan 2017

Abstract excerpt

Understanding the immune response upon infection with the filarial nematode Onchocerca volvulus and the mechanisms that evolved in this parasite to evade immune mediated elimination is essential to expand the toolbox available for diagnostics, therapeutics and vaccines development.Using high-density peptide microarrays we scanned the proteome-wide linear epitope repertoire in Cameroonian onchocerciasis patients...

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PMID: 28125577
DOI: 10.1371/journal.pntd.0005330

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