Article
HLA-DQ alleles associate with cutaneous features of onchocerciasis. The Kaduna-London-Manchester Collaboration for Research on Onchocerciasis.
Human immunology - 1 Jun 1997
Murdoch M E, Payton A, Abiose A, Thomson W, Panicker V K, Dyer P A, Jones B R, Maizels R M, Ollier W E
Abstract excerpt
Onchocerciasis is associated with a spectrum of cutaneous changes, ranging from clinically normal skin to acute and chronic pathology. An important aspect of disease expression may be the level of immune response to parasite antigens, which is likely to be regulated by MHC-encoded molecules. We therefore investigated HLA class I and class II phenotypes in Nigerian residents of an area endemic for onchocerciasis....
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