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Article

An Immunogenic <i>Onchocerca volvulus</i> Antigen: a Specific and Early Marker of Infection

29 Mar 1991

Abstract excerpt

Onchocerciasis (river blindness) is a serious health problem and a severe obstacle to social and economic development, especially in Africa. A complementary DNA fragment coding for an Onchocerca volvulus antigen (OV-16) was cloned and expressed in the plasmid vector pCG808fx. Immune responses to this O. volvulus-specific recombinant antigen were detectable in patients with documented onchocerciasis; the antibody...

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PMID: 2011741
DOI: 10.1126/science.2011741

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An Immunogenic <i>Onchocerca volvulus</i> Antigen: a Specific and Early Marker of InfectionPMID 2011741Read ↗

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