Article
Discrete functional motifs reside within the cytoplasmic tail of alphaV integrin subunit.
Thrombosis and haemostasis - 1 Jan 2008
Haas Thomas A
Abstract excerpt
Previous studies have demonstrated that cell-permeable cytoplasmic tail (CT) alpha(II)beta peptides can modulate the activation of alpha(IIb)b(3). As alpha(V) CT contains an alpha(II)beta homologous region, a series of cell-permeable alpha(V) and alpha(IIb) peptides were generated to determine if alpha(V) CT can modulate the activation of beta(3) integrins in comparison to alpha(IIb), and to identify the minimal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
