Article
Ethnic variation in frequency of an allelic polymorphism of human Fc gamma RIIA determined with allele specific oligonucleotide probes.
Journal of immunological methods - 1 Aug 1994
Osborne J M, Chacko G W, Brandt J T, Anderson C L
Abstract excerpt
We have genotyped 53 individuals from three ethnic groups (Japanese, Chinese, Asian Indian) for an allotypic polymorphism of a widely expressed low affinity Fc receptor for IgG (Fc gamma RIIA). The method, requiring PCR amplification of genomic DNA and Southern analysis with allele specific oligo...
Topics
- Alleles
- Antigens, CD
- Asian People
- Base Sequence
- Blotting, Southern
- China
- DNA
- DNA Primers
- Gene Frequency
- Genetic Variation
- Genetics, Population
- Genotype
- Humans
- India
- Japan
- Molecular Sequence Data
- Ohio
- Oligonucleotide Probes