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Article

Simple detection of large InDeLS by DHPLC: the ACE gene as a model.

Journal of biomedicine & biotechnology - 1 Jan 2008

Koyama Renata Guedes, Castro Rosa M R P S, De Mello Marco Túlio, Tufik Sergio, Pedrazzoli Mario

Abstract excerpt

Insertion-deletion polymorphism (InDeL) is the second most frequent type of genetic variation in the human genome. For the detection of large InDeLs, researchers usually resort to either PCR gel analysis or RFLP, but these are time consuming and dependent on human interpretation. Therefore, a more efficient method for genotyping this kind of genetic variation is needed. In this report, we describe a method that...

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Share to Chromatography, High Pressure Liquid
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Human

Share to Mutagenesis, Insertional

Share to Peptidyl-Dipeptidase A

Share to Sensitivity and Specificity

Share to Sequence Alignment

Share to Sequence Deletion

Source

Open in PubMed Open full text

Identifiers

PMID: 18475319
DOI: 10.1155/2008/562183
PMCID: PMC2358980

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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